Ettema lab blog

Nature News and Views on Asgard cytoskeleton

Laura Eme and Thijs Ettema have co-authored a News and Views highlighting the Nature publication by Akil and Robinson. In this article, the authors performed in vitro experiment on several Asgard profilins and showed that they were able to regulate the polymerization of eukaryotic actin filaments. This suggests that Asgard archaea also have a (perhaps

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Article now available on evolutionary history of archaeal EF2

Slightly delayed announcement due to holidays, but Ettema-Lab has a new paper published in cooperation with Christopher S. Miller (University of Colorado Denver), Brett J. Baker (University of Texas Austin) and Anja Spang (Royal Netherlands Institute for Sea Research). The article in Genome Biology and Evolution describes the complex evolutionary history of translation Elongation Factor 2

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Our new ISME Journal paper on archaeal endosymbionts is out now

Ettema Lab in collaboration with  T. Martin Embley (Newcastle University, UK) just published a new paper in the ISME Journal. In our latest publication, we assembled genomes from two archaeal methanogenic endosymbionts living in closely related anaerobic ciliates. Although the endosymbiont species are not close relatives of one another, their genomes show some similar features that could have

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New Nature publication about the origin of mitochondria

‘Deep mitochondrial origin outside the sampled alphaproteobacteria’ is the brand-new publication in Nature by the Ettema-Lab in collaboration with international partners. This study sought to find the closest living relatives of the mitochondrial ancestor and increased the genomic sample of alphaproteobacteria with 13 previously uncharacterized lineages from the Atlantic and Pacific Ocean. After careful phylogenetic

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New paper available: RNA sequencing of Stentor cell fragments reveals key processes underlying cellular regeneration

Ettema Lab is pleased to announce the new paper in Current Biology by Henning Onsbring Gustafson on cellular regeneration in the ciliate Stentor at single cell resolution. Our new study uses transcriptomics of cell fragments of the ciliate Stentor to reveal the importance of protein phosphorylation, microtubule-based processes and genes involved in the cell cycle for cellular regeneration. Check the paper out here!

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Pre-print available: Comparison of metagenome-assembled and single-amplified genomes

This collaborative study of the Pinhassi-Lab (Linnaeus University, Kalmar), the KTH Royal Inst. of Technology (SciLifeLab, Stockholm) and the Ettema-Lab can now be read as early pre-print at bioRxiv. The paper reports on the comparison of two culture-independent strategies for recovering bacterial genomes: single-amplified genomes and metagenome-assembled genomes, and its implication for in-depth analyses of uncultivated prokaryotic taxa. Read the paper here. /MS

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Nature Microbiology Review is celebrating 40 years of Archaea!

For the 40th anniversary celebration of Archaea at Nature Microbiology Review Ettema Lab is honoured to contribute not only with a review paper but also the cover of this special Dec issue! Our review presents a comprehensive overview regarding the current view of how eukaryotes have evolved from an archaeal ancestor. Join us in the celebration of Archaea

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Just published: Functional reconstruction of a eukaryotic-like ubiquitylation cascade from an uncultured archaeon

The latest publication of the Robinson-lab (Lancaster University, UK) in collaboration with the Ettema-lab is now available online at Nature Communications, regarding the ‘Functional reconstruction of a eukaryotic-like E1/E2/(RING) E3 ubiquitylation cascade from an uncultured archaeon’ – the first time that the ubiquitination cascade has been demonstrated outside of eukaryotes.  You can read the article here. /MS

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Standard and best practices for reporting genomes from metagenomes and single cells

Recently published in Nature Biotechnology Ettema-lab is part of an international cooperation to present two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences. The standards are the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum Information about a Metagenome-Assembled Genome (MIMAG), including, but not limited to,

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Science review: Genomic exploration of the diversity, ecology, and evolution of the archaeal domain of life

Ettema-lab is pleased to announce the recently published Science review ‘Genomic exploration of the diversity, ecology, and evolution of the archaeal domain of life’. Archaea are prokaryotes that make up a third branch of the tree of life. Knowledge of archaeal biological diversity and their role in evolution has rapidly expanded in the past decade. Despite the

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