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- Thijs Ettema
- Post Docs
- PhD Students
After undergraduate studies in Biomedicine at Uppsala University, I stayed on for a PhD in Molecular Medicine under supervision of Prof Ulf Landegren and Dr Masood Kamali-Moghaddam. I defended my thesis, “DNA-mediated detection and profiling of protein complexes” in September 2013. During my PhD I developed methods based on the proximity ligation assay (PLA) to study various kinds of proteins and protein complexes. By using synthetically designed DNA sequences as reporter molecules for proteins, I studied plasma levels of potential biomarker proteins, protein-protein interactions, and aggregates of prion proteins (causing mad cow disease and similar diseases).
Methods development has been a theme for my PhD and previous undergraduate research projects. I joined the Ettema lab as a postdoc in November 2013, with the aim to continue to develop methods to allow asking new questions in biology and biomedicine. More specifically I will develop methods for high throughput single cell genomics (SCG) using a droplet microfluidics platform where single cells can be encapsulated, manipulated and analysed in individual droplets. Collaborating with Helene Andersson Svahn’s research group in the droplet-based SCG project is very exciting for me as I once did my master thesis in this group.